Clinical Features of Acromegaly	

The clinical features of acromegaly (Fig. 3.5) result from (i) over-secretion of GH, which has both clinical and metabolic sequelae, and (ii) effects of the pituitary tumour which are both local and endocrine. Several groups have noted that young patients with acromegaly tend to present with larger tumours, which appear to behave more aggressively, than those that present in patients over the age of fifty years. 

See later:
• Clinical Features of Pituitary Gigantism